Polygenic Contributions to Suicidal Thoughts and Behaviors in a Sample Ascertained for Alcohol Use Disorders.

Sarah M C Colbert,Niamh Mullins,Grace Chan,Jacquelyn L Meyers,Jessica Schulman,Samuel Kuperman,Dongbing Lai,John Nurnberger,Martin H Plawecki,Chella Kamarajan,Andrey P Anokhin,Kathleen K Bucholz,Victor Hesselbrock,Howard J Edenberg,John Kramer,Danielle M Dick,Bernice Porjesz,Arpana Agrawal,Emma C Johnson

Complex psychiatry（2023）

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摘要

Our findings suggest that PRS for depression does not explain the entirety of the variance in suicidal thoughts and behaviors, with PRS specifically for suicidal thoughts and behaviors making additional and sometimes unique contributions.

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关键词

suicidal thoughts,alcohol use disorders,alcohol use,polygenic contributions

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