Circulating IgG Antibodies to Periodontal Bacteria and Lung Cancer Risk in the CLUE Cohorts.

Nana K Ampomah,Flavia Teles,Lynn M Martin,Jiayun Lu,Devin C Koestler,Karl T Kelsey,James D Beck,Elizabeth A Platz,Dominique S Michaud

JNCI cancer spectrum（2023）

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摘要

Findings from this study highlight the complexity of using serum IgG antibodies to periodontal bacteria to identify associations between oral pathogens and risk of lung cancer. The inverse associations observed for antibodies to periodontal bacteria suggest that these may represent markers of immunity that provide some advantage in reducing the development of lung cancer.

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关键词

P. gingivalis,T. denticola,T. forsythia,IgG antibodies,Periodontitis,immune response,lung cancer,periodontal bacteria

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