Identification of Chemokines-Related miRNAs as Potential Biomarkers in Psoriasis Based on Integrated Bioinformatics Analysis.

Haojun Zhuang, Xiaoming Wang,Meiliang Guo,Qinqin Meng,Na Liu,Min Wei,Yuling Shi,Hui Deng

Combinatorial chemistry & high throughput screening（2023）

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摘要

Bioinformatics analysis revealed that the chemokine signalling pathway is involved in the development of psoriasis. Five related miRNAs were mined from the datasets, and qRT-PCR showed that hsa-miR-612 (p=0.0015), hsa-miR-3194-5p (p=0.0078) and hsa-miR-4316 (p<0.0001) may be potential biomarkers in psoriasis.

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关键词

Chemokines,biomarkers,miR-3194-5p,miR-4316,miR-612,microRNAs,psoriasis

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