Disentangling the Causes and Effects of Alcohol Misuse: An Analysis of Resting Electroencephalography Power Spectrum

Identification of hallmarks/features of alcohol misuse (AM) in the brain is challenged by the ‘chicken-and-egg’ question of whether they precede (e.g., genetic predisposition or premorbid environmental exposures) or succeed AM (e.g., cortical atrophy, maladaptive changes in circuitry). To tackle this problem, we analyzed electroencephalography (EEG) from monozygotic twins at ages 18 and 20.