The Current State of PTSD Genetics: Ancestry Informed Analysis Identifies Novel Genetic Risk

Adam Maihofer,Elizabeth Atkinson,Chia-Yen Chen,Karmel Choi,Jonathan Coleman,Nikolaos Daskalakis,Renato Polimanti,Marcos Santoro,Murray Stein,Kerry Ressler,Karestan Koenen,Caroline Nievergelt

Biological Psychiatry（2023）

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摘要

The Psychiatric Genomics Consortium for PTSD has assembled data from over 1.25 million participants, including a diverse collection of over 80,000 individuals of African and Hispanic descent. Here we present a multi-ancestry genome-wide association study (GWAS) of PTSD, highlighting how the ancestral diversity of samples enhances discovery.

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ptsd genetics

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