Step forward in early recognition of systemic sclerosis: data from the Leiden CCISS cohort.

Sophie I E Liem,Jacopo Ciaffi,Nina Marijn van Leeuwen,Maaike Boonstra,Saad Ahmed,Liesbeth J J Beaart-van de Voorde,Anja Corsel,Talitha Dhondai,Maarten K Ninaber,J J Miranda Geelhoed-Veltman,Marlies E Heuvers,Maarten E Tushuizen,Nina Ajmone Marsan,Philippine Kiès,Anne A Schouffoer,Tom W J Huizinga,Cornelia F Allaart,Jeska De Vries-Bouwstra

RMD open（2023）

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摘要

We observed a decrease in disease duration in Leiden CCISS cohort at cohort entry, possibly indicating more timely diagnosis of SSc. This could provide opportunities for early interventions. While symptom duration at presentation is longer in females, mortality is consistently higher in males, underlining the urge for sex-specific treatment and follow-up.

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autoimmunity,patient reported outcome measures,systemic sclerosis

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