The link between chronic cocaine use, B cell perturbations, and blunted immune recovery in HIV-infected individuals on suppressive ART.

Da Cheng,Zhenwu Luo,Sylvia Fitting,William Stoops,Sonya L Heath,Lishomwa C Ndhlovu,Wei Jiang

NeuroImmune pharmacology and therapeutics（2023）

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摘要

This study improves our understanding of cocaine associated B cell perturbations and immune failure and the new appreciation for autoreactive B cells as novel therapeutic targets.

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关键词

CD4+ T cell recovery,HIV,anti-CD4 IgG,antibody-dependent cytotoxicity,antiretroviral therapy,cocaine

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