Activation of the mTORC1 signaling cascade in the hippocampus and medial prefrontal cortex is required for the antidepressant actions of vortioxetine in mice.

The international journal of neuropsychopharmacology(2023)

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摘要
Activation of the mTORC1 system in the hippocampus and medial prefrontal cortex is required for the antidepressant actions of vortioxetine in mice.
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关键词
Chronic social defeat stress,Chronic unpredictable mild stress,Depression,Mammalian target of rapamycin complex 1,Vortioxetine
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