A multiscale computational model of skeletal muscle electroporation validated using in situ porcine experiments.

Rok Smerc,David A Ramirez,Samo Mahnic-Kalamiza,Janja Dermol-Cerne,Daniel C Sigg,Lars M Mattison,Paul A Iaizzo,Damijan Miklavcic

IEEE transactions on bio-medical engineering（2023）

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摘要

The paper presents an important advancement in building up from the current understanding of single cell electroporation to an in silico multiscale model of bulk muscle tissue. The model accounts for anisotropic electrical conductivity and has been validated through experiments in vivo.

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