Ferrocenylmethylation of theophylline

Daniel Weinem, Jana M. Strumberger,Fabian Mohr

ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES（2023）

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摘要

The sodium salt of theophylline is ferrocenylmethylated at N7 in water using [FcCH(2)NMe(3)]I. Further alkylation at N9 with various reagents and under different conditions was however unsuccessful. The molecular structures of both ferrocenylmethylated theophylline and sodium theophyllinate were determined by single crystal X-ray diffraction.

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关键词

ferrocenylmethylation,xanthine,X-ray structure

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