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Best-in-Class Antisense Oligonucleotides Against Hepatitis B Virus Using Next Generation Bridged Nucleic Acid Chemistries Significantly Increases In Vivo Efficacy and Reduces Hepatotoxicity in Mice

Dinah Misner,Jin Hong,Bruno Filippi,Sandra Chang,Monika Tu, Gwendoline Wiki,Friederike Wenz,Kusum Gupta,Vikrant Gohil,Saul Martinez Montero,Vivek K. Rajwanshi,Tse-I Lin,David B. Smith,Julian A. Symons,Lawrence Blatt,Leonid Beigelman,Sushmita Chanda

INTERNATIONAL JOURNAL OF TOXICOLOGY（2023）

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