Quick guide to secondary metabolites from Apiospora and Arthrinium

Marie L. Overgaard,Trine Aalborg,Emil J. Zeuner,Klaus R. Westphal,Frederik A. Lau, Vibeke S. Nielsen, Kasper B. Carstensen, Emil A. Hundeboll, Tia A. Westermann, Gustav G. Rathsach,Jens L. Sorensen,Jens C. Frisvad,Reinhard Wimmer,Teis E. Sondergaard

FUNGAL BIOLOGY REVIEWS(2023)

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摘要
Apiospora and Arthrinium have undergone a period of upheaval with disparate phylogenic affiliation during the past ten years. Recently, they were divided into two separate clades with the majority being Apiospora and several species changing genus from Arthrinum to Apiospora. The first genome annotation became available in 2020, and the potential for novel secondary metabolite production appears very high in these yet unexplored genera compared to other more famous filamentous fungi. In this review, we present the current state of knowledge of 269 secondary metabolites isolated from the two fungal genera combined and highlight some of the compounds with known biological or toxic effects. (c) 2022 British Mycological Society. Published by Elsevier Ltd. All rights reserved.
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关键词
Apiospora,Arthrinium,Secondary metabolism,Non -ribosomal peptide,Polyketide,Terpenoid
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