A New Oleanane-Type Triterpenoid from the Fruits of Chisocheton macrophyllus

Nurlelasari, S. S. Indriani,T. Mayanti,K. Farabi,A. Safari,D. Harneti,R. Maharani,A. T. Hidayat,U. Supratman,D. G. Katja, Y. Shiono

CHEMISTRY OF NATURAL COMPOUNDS（2023）

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摘要

new oleanane-type triterpenoid, 3-oxo-olean-11(12)-en-28-oic acid ( 1 ) and four known oleananes ( 2–5 ), have been isolated from the Chisocheton macrophyllus King fruit. The chemical structures were unambiguously established through extensive spectroscopic data analysis of IR, HR-MS, and NMR. The cytotoxic effect of the compounds was evaluated against MCF-7 and A-549 cells. All compounds had no cytotoxic activity against both cell lines.

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关键词

Chisocheton macrophyllus,Meliaceae,oleananes,cytotoxic activity

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