Aspirin-Exacerbated Respiratory Disease Polymorphisms; a review study

•About 300 million of the world's population have asthma, 20% of whom are middle-aged.•The severity of the disease is reported in women more than in men.•The prevalence of allergic disorders is different between boys and girls.•Recent advances in sequencing the human genome have developed many perspectives for examining the relationship between human polymorphisms and their impact on various diseases.•According to our search in the literature, to date, no study has examined important genetic polymorphisms in AERD. Therefore, due to the unknown genetic factors affecting this disease.