Suppllementary Methods and Supplementary Figures 1-5 from BET Inhibition Induces Apoptosis in Aggressive B-Cell Lymphoma via Epigenetic Regulation of BCL-2 Family Members

Supplementary Methods, Supplementary References, Supplementary Figure 1 - in vitro analysis of various BET inhibitors against Eu-myc lymphoma cells and effect of JQ1 on OPM2 and OPM2/BCL2 cells; Supplementary Figure 2 - In vitro effects of JQ1 on OPM2 and OPM2/BCL2 cells; Supplementary Figure 3 - In vivo effects of JQ1 showing lack of toxicity; Supplementary Figure 4 - induction of Bim in JQ1-sensitive and JQ1-resistant Eu-myc lymphomas; Supplementary Figure 5 - Activated Ras confers resistance to JAK inhibitor and JQ1.