Women Have Greater Endothelin-B Receptor Function and Lower Mitochondrial Capacity Compared to Men with Type 1 Diabetes.

Cassandra C Derella, Jeffery Thomas,Ryan A Harris

The Journal of clinical endocrinology and metabolism（2023）

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摘要

Compared to men with uncomplicated T1D, muscle oxidative capacity was lower and ETBR-mediated vasodilation was higher in women with uncomplicated T1D. ETBR-induced vasodilatory capacity was inversely related to skeletal muscle oxidative capacity, suggesting that there may be compensatory mechanisms occurring to preserve microvascular blood flow in women with T1D.

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endothelin receptors,oxidative capacity,type 1 diabetes

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