miRNA deregulation and relationship with metabolic parameters after Mediterranean dietary intervention in BRCA-mutated women.

Simona De Summa,Debora Traversa,Antonella Daniele,Orazio Palumbo,Massimo Carella,Raffaella Stallone,Antonio Tufaro,Andreina Oliverio,Eleonora Bruno,Maria Digennaro,Katia Danza,Patrizia Pasanisi,Stefania Tommasi

Frontiers in Oncology（2023）

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摘要

We highlighted the synergistic effect of a healthy lifestyle and epigenetic regulation in BC through the modulation of specific miRNAs. Different miRNAs have been reported involved in the tumor onset acting as tumor suppressors by targeting tumor-associated genes that are often downregulated.

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关键词

BRCA,dietary intervention,mediterranean diet,metabolism,miRNA

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