Figure S3 from Reduced CD160 Expression Contributes to Impaired NK-cell Function and Poor Clinical Outcomes in Patients with HCC

Figure S3 shows (A) Cumulative percentage of IFN-γ on sorted CD160- or CD160+ NK cells of peripheral blood; (B) Scatterplot of global gene expression profiles of CD160+ and CD160- NK subsets; (C) Distribution by functional category of up- or down-regulated genes in CD160+ NK cells compared to CD160- NK cells; (D) Overview of functional pathway analysis; (E) Chemokine- or (F) cytokine- related profiles of CD160+ and CD160- NK cells; and (G) GSEA of genes up-regulated in CD160+ NK cells overlapping with gene sets from IL-2-stimulated NK cells, IL-15-stimulated NK cells and CD57- NK cells.