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Physicochemical Characterization and Phase II Metabolic Profiling of Echinochrome A, a Bioactive Constituent from Sea Urchin, and Its Physiologically Based Pharmacokinetic Modeling in Rats and Humans

Dong-Gyun Han,Jinsook Kwak,Eugene Choi,Seong-Wook Seo,Elena A. Vasileva,Natalia P. Mishchenko,Sergey A. Fedoreyev,Valentin A. Stonik,Hyoung Kyu Kim,Jin Han,Jong Hyuk Byun,Il Hyo Jung,Hwayoung Yun,In -Soo Yoon

Biomedicine & Pharmacotherapy（2023）

Cited 3|Views48
Key words
Echinochrome A,Physicochemical characterization,Metabolic profiling,Glucuronidation,Methylation,PBPK model
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