Supplementary Figures 1 - 6 from Phenotypic Profiling of <i>DPYD</i> Variations Relevant to 5-Fluorouracil Sensitivity Using Real-time Cellular Analysis and <i>In Vitro</i> Measurement of Enzyme Activity

PDF file - 497K, Supplementary Figures: 1. Determining the range of linear response for DPD expression and enzyme activity. 2. Analysis of CI profiles using a single analysis time. 3. Establishment of measurement times independently for each culture. 4. Comparison of slope at the toxicity time point. 5. Comparison of slope at the recovery time point. 6. Location of amino acids 534 and 543 within the 5-FU binding pocket of DPD.