Supplementary Figures 1 - 5, Tables 1 - 3 from CD44-Positive Cancer Stem Cells Expressing Cellular Prion Protein Contribute to Metastatic Capacity in Colorectal Cancer

PDF file - 2531K, Supplementary Figure S1. PrPc is correlated with tumor grade, metastasis and outcomes. Supplementary Figure S2. PrPc co-expresses with CD44 and enriches CSC Supplementary Figure S3. PrPc confers greater metastatic capacity in spleen-to-liver metastasis Supplementary Figure S4. PrPc is functional importance for metastatic capacity Supplementary Figure S5. PrPc induces EMT in CCSCs Supplementary Table 1. Analysis of CD44+PrPc+, CD44+PrPc-, CD44-PrPc+, and CD44-PrPc- subpopulations from 31 CRC patients Supplementary Table 2. Tumor-initiating incidence of CD44+PrPc+, CD44+PrPc-, CD44-PrPc+ and CD44-PrPc- CRC subpopulations Supplementary Table 3. Primers for quantitative PCR