Supplementary Figures 1-10 from Unexpected Dissemination Patterns in Lymphoma Progression Revealed by Serial Imaging within a Murine Lymph Node

PDF file - 2.5MB, Supplementary Figure 1. Comparison between parental cells and EGFP/Luc-transfected Arf-/- (EL-Arf-/-) lymphoma cells in cell growth and apoptosis sensitivity Supplementary Figure 2. Angiogenesis development in the ILN Supplementary Figure 3. Ex vivo bioluminescence analysis at day 7 Supplementary Figure 4. Comparison of bioluminescence intensity by different injection number of EL-Arf-/- cells. Supplementary Figure 5. Representative bioluminescence imaging of N=5 mice after direct injection of EL-Arf-/- lymphoma cells into the spleen. Supplementary Figure 6. Efflux of EL-p53-/- lymphoma cells from the spleen and Bone Marrow (BM) to the periphery in the middle stage Supplementary Figure 7. Quantitation of EGFP signal in a field of ILN obtained with the LNIWC. Supplementary Figure 8. Lymph node internal window chamber images in EL-p53-/- lymphoma cell injected mice. Supplementary Figure 9. H&E and Proliferation (Ki-67) staining on day 14 in Arf-/-. Supplementary Figure 10. IVM images in the ILN employing the skin side lymph node window chamber (LNWC) and conventional tissue flap approach.