Supplementary Table 1, Figures 1 - 8 from PLA2R1 Mediates Tumor Suppression by Activating JAK2

PDF file - 326K, Supplementary Figure 1: The knockdown of PLA2R1 favors OIS escape. Supplementary Figure 2: The knockdown of PLA2R1 favors transformation. Supplementary Figure 3: The knockdown of PLA2R1 favors OIS escape in human normal keratinocytes. Supplementary Figure 4: DMBA/TPA treatment induces senescence and its escape correlates with papillomas formation. Supplementary Figure 5: Validation of H-Ras mutation in papilloma. Supplementary Figure 6: JAK2 is involved in PLA2R1-mediated cell growth regulation. Supplementary Figure 7: PLA2R1 regulates JAK2 activity. -Supplementary Figure 8: JAK2 mediates PLA2R1 tumor suppressive effects.