Supplemental Figures 1 - 6 from Oncogenic PI3K Mutations Lead to NF-κB–Dependent Cytokine Expression following Growth Factor Deprivation

Figure S1: Quantification of data from Figure 1A. Figure S2: A subset of PI3K-driven genes is regulated by NF-κB. Figure S3: IKK inhibition decreases secretion of IL-6 and CXCL1. Figure S4: IKK inhibition does not decrease cell metabolic activity or susceptibility to apoptosis. Figure S5: Quantification of data from Figure 6. Figure S6: IL-6 receptor inhibition does not decrease proliferation of MCF10A cells expressing PIK3CA E545K.