Supplementary Figures 1 - 5 from Oxidative Stress Activates SIRT2 to Deacetylate and Stimulate Phosphoglycerate Mutase

PDF file - 104KB, Characterization of anti-acetyl-PGAM2(K100) antibody (S1). The endogenous activity of PGAM correlates with K100 acetylation level in different tissues (S2). Acetylation of K100 doesn't affect PGAM dimerization (S3). SIRT2 deacetylates PGAM2 (S4). NAM, but not TSA, decreases PGAM2 enzyme activity (S5).