Construction and Application of Multipurpose metal-organic frameworks -based Hydrogen Sulfide Probe

Hydrogen sulfide (H 2 S) is a toxic gas derived from the sulfur industry and trace H 2 S in the environment can cause serious ecological damage while inhalation can cause serious damage and lead to disease. Therefore, the real-time and accurate detection of trace sulfur ions is of great significance for environmental protection and early disease detection. Considering the shortcoming of current H 2 S probes in terms of stability and sensitivity, the development of novel probes is necessary. Herein, a novel metal-organic frameworks (MOF)-based material, UiO-66-NH 2 @BDC, was designed and prepared for the visual detection of H 2 S with rapid response (< 6 s) and low detection limit of S 2− (0.13 µM) by hydrogen bonding. Based on its good optical performance, the UiO-66-NH 2 @BDC probe can detect S 2− in various water environments. More importantly, UiO-66-NH 2 @BDC probe realize imaging S 2− in cells and live zebrafish.