sCD14 and intestinal fatty acid binding protein are elevated in the serum of patients with idiopathic anaphylaxis.

Vivian T Cao,Melody C Carter,Jason M Brenchley,Hyejeong Bolan,Linda M Scott,Yun Bai,Dean D Metcalfe,Hirsh D Komarow

The journal of allergy and clinical immunology. In practice（2023）

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摘要

I-FABP and sCD14 are elevated in the serum of patients with IA. Elevations in these biomarkers of IA provides evidence that increased gastrointestinal permeability, as is observed in other allergic conditions such as food allergy, is a common finding in those with IA and offers possible insight into the pathogenesis of this disease.

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关键词

I-FABP,epithelial barrier,idiopathic anaphylaxis,mastocytosis,microbial translocation,soluble CD14,zonulin

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