Supplementary Information from Nrf2 Mutagenic Activation Drives Hepatocarcinogenesis

Supplementary Materials and Methods. Supplementary figures: Figure S1. Genotyping of WT and Nrf2 KO mice; Figure S2. Nrf2 KO mice do not exhibit hepatic anomalies; Figure S3. Glut1 is upregulated by Nrf2 in the livers of DEN-treated mice; Figure S4. Nrf2 induces upregulation of hepatic antioxidant gene expression in the DEN-treated mice; Figure S5. Mutations in Nrf2 are associated with an inferior survival. Supplementary tables: Table S1. The sequences of primers used for genotyping; Table S2. The sequences of primers used for qPCR; Table S3. The primers used for identifying mutations in Nrf2; Table S4. The sequences of primers used for constructing plasmids and site-directed mutagenesis study.