Supplemental Figure 1-5 from IFNγ-induced Chemokines Are Required for CXCR3-mediated T-Cell Recruitment and Antitumor Efficacy of Anti-HER2/CD3 Bispecific Antibody

Fig. S1. Subset analysis of tumor infiltrating and splenic CD8+ T cells after treatment with anti-HER2/CD3 TDB; Fig. S2. Anti-HER2/CD3 TDB increases intra-tumoral lymphocyte infiltration in Fo5 allograft model of HER2 overexpressing breast cancer within immunocompetent mice; Fig. S3. Anti-HER2/CD3 treatment did not induce peripheral CD8+ T cell proliferation; Fig. S4. Anti-HER2/CD3 TDB induced acute release of pro-inflammatory cytokines in serum; Fig. S5. Induction of CXCR3 ligands within Fo5 tumors in response to anti-HER2/CD3.