Supplementary Figures S1 and S2 and Supplementary Tables S1 and S2 from Changes in Bone Turnover Marker Levels and Clinical Outcomes in Patients with Advanced Cancer and Bone Metastases Treated with Bone Antiresorptive Agents

Supplementary Figure S1: Combined patient population and treatments in the three phase III studies included in the analysis. Supplementary Figure S2: OS (A), DP (B), and DPB (C) stratified by category ({greater than or equal to} or < median) of month 3 sBSAP percent change from baseline. Supplementary Table S1: BTM levels at baseline and at month 3 after bone antiresorptive treatment. Supplementary Table S2: Covariate analysis of OS, DP, and DPB at month 3 adjusted for baseline visceral metastases, bone metastases, or ECOG category.