The Ala307Thr polymorphism of the follicle-stimulating hormone receptor (FSHR) gene is associated with the dose of recombinant FSH received during IVF/ICSI treatment.

Felipe Dieamant,Claudia Guilhermino Petersen,Laura Diniz Vagnini,Bruna Petersen,Juliana Ricci,Andreia Nicoletti,Camila Zamara,Antonio Helio Oliani,Joao Batista A Oliveira,José G Franco

JBRA assisted reproduction（2023）

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摘要

The Ala/Ala genotype was associated with the use of higher doses of recombinant FSH (r-FSH), suggesting that homozygosis of this allelic variant (Ala) provides lower sensitivity to r-FSH.

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关键词

Ala307Thr polymorphism,FSH,FSHR gene,ovarian response,ovarian stimulation

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