Effect of vericiguat on left ventricular structure and function in patients with heart failure with reduced ejection fraction: the VICTORIA echocardiographic substudy.

Burkert Pieske,Elisabeth Pieske-Kraigher,Carolyn S P Lam,Vojtěch Melenovský,Karen Sliwa,Yuri Lopatin, Juan Luis Arango,M Cecilia Bahit,Christopher M O'Connor,Mahesh J Patel,Lothar Roessig,Daniel A Morris,Martin Kropf,Cynthia M Westerhout,Yinggan Zheng,Paul W Armstrong

European journal of heart failure（2023）

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摘要

In this pre-specified echocardiographic study, significant improvements in LV structure and function occurred over 8 months in both vericiguat and placebo in a high-risk HFrEF population with recent worsening HF. Further studies are warranted to define the mechanisms of vericiguat's benefit in HFrEF.

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关键词

Echocardiography,Heart failure with reduced ejection fraction,Left ventricular function,Left ventricular structure,Vericiguat

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