Single-Cell RNA-Sequencing Analysis Reveals Divergent Transcriptome Events between Platinum-Sensitive and Platinum-Resistant High-Grade Serous Ovarian Carcinoma.

Zixun Wang,Linlin Yang, Xiaoye Su,Xiaomei Wu,Rongjia Su

The journal of gene medicine（2023）

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摘要

Our study presents a view of HGSC at single-cell resolution that reveals the characteristics of the HGSC heterogeneity and provided a useful framework for future investigation of platinum-resistant.

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关键词

EMT,HGSC,platinum resistance,scRNA-seq,tumor heterogeneity

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