Supplementary figures 1 and 3-6 from Androgen and Estrogen Receptors in Breast Cancer Coregulate Human UDP-Glucuronosyltransferases 2B15 and 2B17

Supplementary Figure 1. Correlation plots depicting the relationship between UGT2B15 and UGT2B17 mRNA expression in breast cancer. Supplementary Figure 3. Steroid-mediated regulation of GREB1, UGTB215 and UGTB17 in MCF7 cells. Supplementary Figure 4. Effect of ERα, FOXA1 or AR knockdown on UGT2B15 and UGT2B17 mRNA expression in MCF7 cells. Supplementary Figure 5. Genome browser images of showing FOXA1, ERα and AR chromatin occupancy at the UGT2B15 and UGT2B17 promoters in ZR75-1 and MCF7 cells. Supplementary Figure 6. Regulation of UGT2B15 and UGT2B17 mRNA expression by the AR agonist Enobosarm in MCF7 cells (A and B) and steroid-mediated regulation of UGT2B15 and UGT2B17 mRNA expression in normal breast tissues (C).