Enhanced Intestinal Permeability of Cefixime by Self-Emulsifying Drug Delivery System: In-Vitro and Ex-Vivo Characterization.

Arshad Mahmood, Laraib Khan,Muhammad Ijaz,Imran Nazir, Mahrukh Naseem,Muhammad Azam Tahir,Muhammad Naeem Aamir,Masood Ur Rehman,Mulazim Hussain Asim

Molecules (Basel, Switzerland)（2023）

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摘要

Owing to the significantly improved drug solubility, in vitro release and better antibacterial activity, it can be assumed that CFX-loaded SEDDS might lead to an increased bioavailability and antibacterial activity, possibly leading to improved therapeutic effectiveness.

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关键词

cefixime,oral bioavailability,permeation enhancement,self-nanoemulsifying drug delivery system (SEDDS)

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