An Artificial Placenta Experimental System in Sheep: Critical Issues for Successful Transition and Survival up to One Week.

Elisenda Eixarch,Miriam Illa,Raquel Fucho,Kambiz Rezaei,Ameth Hawkins-Villarreal,Sara Bobillo-Pérez,Paula C Randanne, Miguel Moran,Marina Chorda,Sergio Sanchez-Martinez,Yolanda J D de Roo-Puente, Maria Del Mar Velilla,Ruth Del Rio, Marc Gallego,Daniel Sanin-Ramirez, Victor Narvaez,Fatima Crispi,Elisenda Bonet-Carne,Eduard Gratacos

Biomedicines（2023）

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摘要

Achieving a reproducible experimental setting for an AP system is extremely challenging, time- and effort-consuming, and requires a highly multidisciplinary team. As a result of the learning curve, we achieved reproducible transition and survival up to 7 days. Extended survival requires improving instrumentation with custom-designed devices.

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关键词

artificial placenta,artificial womb,fetal lamb

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