The Effects of Topiroxostat, a Selective Xanthine Oxidoreductase Inhibitor, on Arterial Stiffness in Hyperuricemic Patients with Liver Dysfunction: A Sub-Analysis of the BEYOND-UA Study.

Yuya Fujishima,Hitoshi Nishizawa,Yusuke Kawachi,Takashi Nakamura,Seigo Akari, Yoshiyuki Ono,Shiro Fukuda,Shunbun Kita,Norikazu Maeda,Satoshi Hoshide,Iichiro Shimomura,Kazuomi Kario

Biomedicines（2023）

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摘要

Topiroxostat improved arterial stiffness parameters in hyperuricemic patients with liver dysfunction, which might be related to its inhibitory effect on plasma XOR.

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关键词

arterial stiffness,hypertension,hyperuricemia,liver dysfunction,xanthine oxidoreductase inhibitors

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