Local Recurrence After Breast-Conserving Therapy in Patients With Multiple Ipsilateral Breast Cancer: Results From ACOSOG Z11102 (Alliance).

Judy C Boughey,Kari M Rosenkranz,Karla V Ballman,Linda McCall,Bruce G Haffty,Laurie W Cuttino,Charlotte D Kubicky,Huong T Le-Petross,Armando E Giuliano,Kimberly J Van Zee,Kelly K Hunt,Olwen M Hahn,Lisa A Carey,Ann H Partridge

Journal of clinical oncology : official journal of the American Society of Clinical Oncology（2023）

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摘要

The Z11102 clinical trial demonstrates that breast-conserving surgery with adjuvant radiation that includes lumpectomy site boosts yields an acceptably low 5-year LR rate for MIBC. This evidence supports BCT as a reasonable surgical option for women with two to three ipsilateral foci, particularly among patients with disease evaluated with preoperative breast MRI.

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