Combination therapy for patent ductus arteriosus in preterm infants: Echocardiographic changes and clinical use

Ayman Saker,Aimann Surak,Susan Kimani,Andrea De La Hoz,Michael R. Miller,Renjini Lalitha,Soume Bhattacharya

Progress in Pediatric Cardiology（2023）

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摘要

•Combination of ibuprofen and acetaminophen is a novel approach for PDA treatment.•Echocardiographic parameters relating to hsPDA improved with primary course of combination therapy in study cohort.•Future studies exploring the safety and efficacy of combination therapy as a primary treatment for PDA are warranted.

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Combination therapy,Neonates,Patent ductus arteriosus,Echocardiography

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