Frontoparietal 18F-FDG-PET hypo-metabolism in Lennox-Gastaut syndrome: further evidence highlighting the key network

Tom Balfroid,Aaron E.L. Warren,Linda J. Dalic,Alec Aeby,Salvatore U. Berlangieri,John S. Archer

Epilepsy Research（2023）

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摘要

Interictal hypometabolism in frontoparietal cortex in LGS is compatible with our previous EEG-fMRI and SPECT studies showing that interictal bursts of generalised paroxysmal fast activity and tonic seizures recruit similar cortical regions. This study provides further evidence that these regions are central to the electroclinical expression of LGS.

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