Mosaic Loss of Y Chromosome in White Blood Cells: Its Impact on Men's Health

PHYSIOLOGY（2023）

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摘要

We present a brief introduction of loss of Y chromosome (LOY) in blood and describe the known risk factors for this condition. We then overview the associations between LOY and age-related disease traits. Finally, we discuss murine models and the potential mechanisms by which LOY contributes to disease.

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关键词

white blood cells,mosaic loss

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