Exposure to cigarette smoke triggers proteolytic cleavage of occludin, a tight junction protein, by cathepsin S and impairs the pulmonary epithelial barrier during COPD

P. Bigot, S. Chesseron,A. Saidi, D. Sizaret, A. Petit-Courty,Y. Courty, F. Lecaille,G. Lalmanach

Revue des Maladies Respiratoires(2023)

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关键词
Cysteine protease,Chronic obstructive pulmonary disease (COPD),Epithelial barrier,Inflammation,Tight junction protein
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