Skeletal Muscle Bioenergetics in Critical Limb Ischemia and Diabetes.

Victoria G Rontoyanni,Elizabeth Blears,Omar Nunez Lopez,John Ogunbileje,Tatiana Moro,Nisha Bhattarai,Amanda C Randolph,Christopher S Fry,Grant T Fankhauser,Zulfiqar F Cheema,Andrew J Murton,Elena Volpi,Blake B Rasmussen,Porter Craig

The Journal of surgical research（2023）

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摘要

Skeletal muscle mitochondrial respiratory capacity was blunted by ∼35% in patients with CLI. T2DM was not associated with muscle oxidative capacity and did not moderate the relationship between muscle mitochondrial respiratory capacity and CLI.

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关键词

Critical limb ischemia,Diabetes,Mitochondria,Oxidative phosphorylation,Peripheral artery disease

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