P66shc in the spinal cord is an important contributor in complete Freund's adjuvant induced inflammatory pain in mice.

Qianqian Chen,Juji Dai, Fubei Nan,Jun Xu,Shuangdong Chen

Biochemical and biophysical research communications(2023)

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摘要
Spinal p66shc may facilitate the development of inflammatory pain by promoting the activation of NLRP3 inflammasome through ROS.
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关键词
Inflammatory pain,NLRP3 inflammasome,ROS,p66shc
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