Immune response to BNT162b2 SARS-CoV-2 vaccine in patients living with HIV: The COVIH-DAPT study.

Sabrina Manni,Caroline Ruetsch,Roxane Fabre,Michel Ticchioni,Daisy Graça,Christian Pradier,Barbara Seitz-Polski,Laurene Lotte,Vesna Brglez,Matteo Vassallo

Frontiers in immunology（2023）

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摘要

PLWH have a robust immune response after SARS-CoV-2 vaccination, but a rapid decline in humoral response from 3 months onwards, due to a blunted memory B cell response. Analysis of lymphocyte subsets may help identify optimal times for vaccine boosters.

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关键词

HIV,SARS-CoV-2,immune response,lymphocyte subsets,vaccine

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