Initial Evidence for the Efficacy of Naporafenib in Combination With Trametinib in NRAS -Mutant Melanoma: Results From the Expansion Arm of a Phase Ib, Open-Label Study.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology（2023）

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摘要

Naporafenib plus trametinib showed promising preliminary antitumor activity in patients with -mutant melanoma. Prophylactic strategies aimed to lower the incidence of skin-related events are under investigation.

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关键词

naporafenib,melanoma,trametinib,open-label

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