Central sensitization in CRPS patients with widespread pain: A cross-sectional study.

Iara De Schoenmacker, Anna Mollo,Paulina Simonne Scheuren,Laura Sirucek,Florian Brunner,Petra Schweinhardt,Armin Curt,Jan Rosner,Michèle Hubli

Pain medicine (Malden, Mass.)（2023）

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摘要

Overall, we provide evidence that the pain phenotype in CRPS, i.e., spatial pain extent, might be related to sensitization mechanism within the central nociceptive system. This study points towards central neuronal excitability as a potential therapeutic target in patients with more widespread CRPS.

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关键词

central sensitization,complex regional pain syndrome,quantitative sensory testing,spatial pain extent,temporal summation of pain

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