Clinical Features of Genetic Resilience in Chronic Obstructive Pulmonary Disease.

Auyon J Ghosh,Matthew Moll,Jonathan Hess,Brian D Hobbs, Angela Love,Liam Coyne,Michael H Cho,Peter Castaldi,Frank A Middleton,Andras Perl,Edwin K Silverman,Craig P Hersh,Stephen J Glatt

medRxiv : the preprint server for health sciences（2023）

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摘要

Genetically resilient individuals had a reduced burden of COPD disease-related measures compared to risk-matched cases but had subtly increased measures compared to low-risk unaffected individuals. Further genetic studies will be needed to illuminate the underlying pathobiology of our observations.

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