Maternal and fetal origins of offspring blood pressure: statistical analysis using genetic correlation and genetic risk score-based Mendelian randomization.

Siyi Jin,Ting Wang,Chen Wenying,Yuxuan Wu,Shuiping Huang,Ping Zeng

International journal of epidemiology（2023）

引用 3|浏览33

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摘要

This study revealed common genetic components underlying birthweight and blood pressure, and provided important insight into aetiology and early prevention of high blood pressure.

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关键词

Blood pressure,Mendelian randomization,birthweight,genetic risk score,instrumental variable,intrauterine environment,maternal/fetal-specific genetic effect,pleiotropy analysis,summary statistics

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