Regulatory safety assessment of nanoparticles for the food chain in Europe

Reinhilde Schoonjans,Jacqueline Castenmiller,Qasim Chaudhry,Francesco Cubadda, Takis Daskaleros,Roland Franz,David Gott,Jan Mast,Alicja Mortensen,Agnes G. Oomen,Hubert Rauscher,Stefan Weigel,Maria Chiara Astuto,Irene Cattaneo,Eric Barthelemy,Ana Rincon,José Tarazona

Trends in Food Science & Technology（2023）

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摘要

•EFSA has established hypothesis driven guidance for nanoscale assessments.•This innovation is applicable to chemicals in EU food and feed safety assessments.•This ensures consumer protection, independently of nanomaterial definitions.•Alternatives to animal testing support these Next Generation Risk Assessments.•Cases of actual implementation in EFSA assessments are presented.

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关键词

Nanomaterial,Particulate material,Risk assessment,Physicochemical characterisation,Toxicity testing,Integrated approaches to testing and assessment (IATA)

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